Dual role of the activated epidermal growth factor receptor in renal tubular cells during stress
نویسندگان
چکیده
منابع مشابه
Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor.
Repair of injured renal epithelium is thought to be mediated by surviving renal proximal tubular cells (RPTC) that must dedifferentiate to allow the proliferation and migration necessary for epithelial regeneration. RPTC then redifferentiate to restore tubular structure and function. Current models suggest that epidermal growth factor receptor (EGFR) activation is required for dedifferentiation...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2008
ISSN: 0085-2538
DOI: 10.1038/sj.ki.5002583